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中國醫(yī)學科學院/北京協(xié)和醫(yī)學院病原生物學研究所黨委副書記、紀委書記、課題組組長。全國結(jié)核病防治綜合質(zhì)量控制專家指導委員會委員、中國免疫學會感染免疫分會委員、中國防癆協(xié)會結(jié)核病基礎(chǔ)專業(yè)分會常委?！吨腥A結(jié)核和呼吸雜志》和《結(jié)核與肺部疾病雜志》編委。
主要研究方向是感染、炎癥與免疫機制研究。主持或參與國家科技重大專項、國家重點研發(fā)計劃、國家自然科學基金、醫(yī)學與健康科技創(chuàng)新工程等多項國家級和院校級科研項目，參與多項戰(zhàn)略咨詢項目研究。在SCI收錄雜志上發(fā)表學術(shù)論文30余篇；獲得6項發(fā)明專利授權(quán)；獲得中華醫(yī)學科學技術(shù)獎二等獎（排名第五）、重大專項創(chuàng)新團隊獎。

結(jié)核病等我國重大傳染病免疫機制及新型生物標識的研究。

1.    國家重點研發(fā)計劃（2021-2026），結(jié)核病新型診斷、治療、干預手段及產(chǎn)品研發(fā)，課題骨干。
2.    中國醫(yī)學科學院中央級公益性科研院所基本科研業(yè)務費（2020-2022），西藏自治區(qū)結(jié)核病流行菌株特征及致病特點研究，課題負責人。
3.    國家自然科學基金委員會面上項目（2021-2024），血管生成素2參與活動性肺結(jié)核免疫機制研究，課題負責人。
4.    中國工程院咨詢研究項目(2019-2020 )，中國與法國等發(fā)達國家結(jié)核病防治體系的對比研究，課題骨干。
5.    國家外專局高端外國專家項目(2018-1019)，結(jié)核病新型分子標識研究，課題負責人。
6.    國家科技重大專項 (2017-2020)，菌陰結(jié)核病和結(jié)核分枝桿菌潛伏感染相關(guān)生物標志物研究，子課題負責人。
7.    中國醫(yī)學科學院醫(yī)學與健康科技創(chuàng)新工程項目(2016-2021)，感染性疾?。ńY(jié)核病等）診治新策略研究，課題骨干。
8.    國家自然科學基金委員會面上項目(2012-2015)，接頭蛋白Gab2調(diào)控結(jié)核病發(fā)生、發(fā)展的免疫學功能研究，課題負責人。
9.    國家科技重大專項 (2012-2015)，結(jié)核病分子標識的研究，課題負責人。
10.    國家科技重大專項(2008-2010)，結(jié)核病免疫保護機制研究，課題負責人。
11.    國家科技重大專項 (2008-2010)，結(jié)核病診斷分子標識研究，子課題負責人。

1.    Dong, H., Y. Zhang, Y. Zou, Y. Chen, J. Yue, H. Liu and X. Jiang (2021). "Elevated chemokines concentration is associated with disease activity in Takayasu arteritis." Cytokine 143: 155515.
2.    Li, H., L. Liu, W. J. Zhang, X. Zhang, J. Zheng, L. Li, X. Zhu, Q. Yang, M. Zhang, H. Liu, X. Chen and Q. Jin (2019). "Analysis of the Antigenic Properties of Membrane Proteins of Mycobacterium tuberculosis." Sci Rep 9(1): 3042.
3.    Liu, C. H., H. Liu and B. Ge (2017). "Innate immunity in tuberculosis: host defense vs pathogen evasion." Cell Mol Immunol 14(12): 963-975.
4.    Hu, Y., Y. Zhang, X. Ren, Y. Liu, Y. Xiao, L. Li, F. Yang, H. Su, F. Liu, H. Liu, B. Cao and Q. Jin (2016). "A case report demonstrating the utility of next generation sequencing in analyzing serial samples from the lung following an infection with influenza A (H7N9) virus." J Clin Virol 76: 45-50.
5.    Yu, Y., D. Jin, S. Hu, Y. Zhang, X. Zheng, J. Zheng, M. Liao, X. Chen, M. Graner, H. Liu and Q. Jin (2015). "A novel tuberculosis antigen identified from human tuberculosis granulomas." Mol Cell Proteomics 14(4): 1093-1103.
6.    Zhang, M., G. Zeng, Q. Yang, J. Zhang, X. Zhu, Q. Chen, P. Suthakaran, Y. Zhang, Q. Deng, H. Liu, B. Zhou and X. Chen (2014). "Anti-tuberculosis treatment enhances the production of IL-22 through reducing the frequencies of regulatory B cell." Tuberculosis (Edinb) 94(3): 238-244.
7.    Liu, L., W. J. Zhang, J. Zheng, H. Fu, Q. Chen, Z. Zhang, X. Chen, B. Zhou, L. Feng, H. Liu and Q. Jin (2014). "Exploration of novel cellular and serological antigen biomarkers in the ORFeome of Mycobacterium tuberculosis." Mol Cell Proteomics 13(3): 897-906.
8.    Hu, S., Y. Zhang, Y. Yu, D. Jin, X. Zhang, S. Gu, H. Jia, X. Chen, Z. Zhang, Q. Jin, Y. Ke and H. Liu (2014). "Growth factor receptor bound protein 2-associated binder 2, a scaffolding adaptor protein, negatively regulates host immunity against tuberculosis." Am J Respir Cell Mol Biol 51(4): 575-585.
9.    Zhang, Y., H. Liu, L. Wang, F. Yang, Y. Hu, X. Ren, G. Li, Y. Yang, S. Sun, Y. Li, X. Chen, X. Li and Q. Jin (2013). "Comparative study of the cytokine/chemokine response in children with differing disease severity in enterovirus 71-induced hand, foot, and mouth disease." PLoS One 8(6): e67430.
10.    Yu, Y., Y. Zhang, S. Hu, D. Jin, X. Chen, Q. Jin and H. Liu (2012). "Different patterns of cytokines and chemokines combined with IFN-gamma production reflect Mycobacterium tuberculosis infection and disease." PLoS One 7(9): e44944.
11.    Qiu, Z., M. Zhang, Y. Zhu, F. Zheng, P. Lu, H. Liu, M. W. Graner, B. Zhou and X. Chen (2012). "Multifunctional CD4 T cell responses in patients with active tuberculosis." Sci Rep 2: 216.
12.    Liu, K., Y. Zhang, S. Hu, Y. Yu, Q. Yang, D. Jin, X. Chen, Q. Jin and H. Liu (2012). "Increased levels of BAFF and APRIL related to human active pulmonary tuberculosis." PLoS One 7(6): e38429.
13.    Zhang, M., Z. Wang, M. W. Graner, L. Yang, M. Liao, Q. Yang, J. Gou, Y. Zhu, C. Wu, H. Liu, B. Zhou and X. Chen (2011). "B cell infiltration is associated with the increased IL-17 and IL-22 expression in the lungs of patients with tuberculosis." Cell Immunol 270(2): 217-223.
14.    Bai, X., K. Chmura, A. R. Ovrutsky, R. P. Bowler, R. I. Scheinman, R. E. Oberley-Deegan, H. Liu, S. Shang, D. Ordway and E. D. Chan (2011). "Mycobacterium tuberculosis increases IP-10 and MIG protein despite inhibition of IP-10 and MIG transcription." Tuberculosis (Edinb) 91(1): 26-35.
15.    Chen, X., M. Zhang, X. Zhu, Q. Deng, H. Liu, N. Larmonier, M. W. Graner and B. Zhou (2009). "Engagement of Toll-like receptor 2 on CD4(+) T cells facilitates local immune responses in patients with tuberculous pleurisy." J Infect Dis 200(3): 399-408.
16.    Niedbala, W., B. Cai, H. Liu, N. Pitman, L. Chang, and F.Y. Liew, Nitric oxide induces CD4+CD25+ Foxp3 regulatory T cells from CD4+CD25 T cells via p53, IL-2, and OX40. Proc Natl Acad Sci U S A, 2007. 104(39): p. 15478-83.
17.    Liu, H. and B.P. Leung, CD4+CD25+ regulatory T cells in health and disease. Clin Exp Pharmacol Physiol, 2006. 33(5-6): p. 519-24.
18.    Liu, H., M. Komai-Koma, D. Xu, and F.Y. Liew, Toll-like receptor 2 signaling modulates the functions of CD4+ CD25+ regulatory T cells. Proc Natl Acad Sci U S A, 2006. 103(18): p. 7048-53.
19.    Liew, F.Y., H. Liu, and D. Xu, A novel negative regulator for IL-1 receptor and Toll-like receptor 4. Immunol Lett, 2005. 96(1): p. 27-31.
20.    Xu, D., H. Liu, and M. Komai-Koma, Direct and indirect role of Toll-like receptors in T cell mediated immunity. Cell Mol Immunol, 2004. 1(4): p. 239-46.
21.    Brint, E.K., D. Xu, H. Liu, A. Dunne, A.N. McKenzie, L.A. O'Neill, and F.Y. Liew, ST2 is an inhibitor of interleukin 1 receptor and Toll-like receptor 4 signaling and maintains endotoxin tolerance. Nat Immunol, 2004. 5(4): p. 373-9
22.    Xu, D., H. Liu, M. Komai-Koma, C. Campbell, C. McSharry, J. Alexander, and F.Y. Liew, CD4+CD25+ regulatory T cells suppress differentiation and functions of Th1 and Th2 cells, Leishmania major infection, and colitis in mice. J Immunol, 2003. 170(1): p. 394-9.
23.    Liu, H., B. Hu, D. Xu, and F.Y. Liew, CD4+CD25+ regulatory T cells cure murine colitis: the role of IL-10, TGF-beta, and CTLA4. J Immunol, 2003. 171(10): p. 5012-7.

培養(yǎng)博士研究生4名，碩士研究生4名，3名碩士研究生在讀。